Serum hydroxybutyrate dehydrogenase and COVID-19 severity and mortality: a systematic review and meta-analysis with meta-regressionArticle Published on 2022-11-012022-11-15 Journal: Clinical and experimental medicine [Category] 바이오마커, [키워드] 95% CI Admission alteration Analysis Biomarker certainty of evidence Concentration conducted coronavirus disease COVID-19 COVID-19 patients COVID-19 severity disease severity effect size Egger estimates heterogeneity hospitalized COVID-19 patient hydroxybutyrate hydroxybutyrate dehydrogenase Inflammation Injury Liver damage magnitude marker Meta-analysis meta-regression moderate Mortality mortality. Myocardial myocardial injury non-specific non-survivor Patient performed renal renal function reported risk stratification searched Sepsis serum severity significantly significantly higher SMD standardized mean difference survival survivor systematic review tissue damage Web of Science [DOI] 10.1007/s10238-021-00777-x PMC 바로가기
Lipidomics Revealed Plasma Phospholipid Profile Differences between Deceased and Recovered COVID-19 PatientsArticle Published on 2022-10-152022-11-15 Journal: Biomolecules [Category] 진단, [키워드] abnormality addition analyzed Anemia appear autoantibody changes characterized control group coronavirus COVID-19 COVID-19 patients CRP level Deceased decrease difference disorder disorders FIVE healthy immune system increase in Increased LDH Lipidomics Liver damage low-density Low-density lipoprotein majority Modification oxidative oxidative stress pathophysiological Patient patients Phosphatidylcholine Phosphatidylserine phospholipid Phospholipids plasma plasma. profile profiles Prognostic value recovered recovered patient recovered patients reported Revealed SARS-CoV-2 significantly two subgroup [DOI] 10.3390/biom12101488 PMC 바로가기
COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment managementReview article Published on 2022-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome addition aggravate Asymptomatic caused Characteristics chronic liver disease cirrhosis clinical clinical manifestation Complication Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient Critical death disease dysfunction Epidemic extrapulmonary organs Factors hepatic function Hepatocellular carcinoma hypoxia immune increased risk infection with SARS-CoV-2 inflammatory factor storms Injury liver Liver damage Liver disease liver enzyme Liver function Liver injury liver transplant Liver transplantation management mechanism nonalcoholic fatty liver pathophysiological mechanism Patient patients prevalent public health reperfusion Respiratory disease risk SARS-CoV-2 severe disease Stress Treatment Vaccine [DOI] 10.1016/j.biopha.2022.113568 [Article Type] Review article
SARS-CoV-2 induced hepatic injuries and liver complicationsArticle Published on 2022-09-162022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 진단, 치료기술, [키워드] abnormality acute respiratory syndrome ADE Affect Antibody-dependent enhancement Case fatality rate caused clinician Comorbidity Complication Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 pandemic COVID-19 patient demonstrated detectable diabetes disease Effect Fecal sample gastrointestinal tract globe HCC hepatic dysfunction hepatic injury hepatocellular Hepatocellular carcinoma hepatocyte highly pathogenic hypertension hypoxia identification Immunopathogenesis in vitro in vivo Infection investigated involved Ischemia liver Liver damage Liver injury mechanism mechanism of liver damage. molecular mechanism multifactorial Patient Psychological reported Research Respiratory samples rising RNA RT-PCR SARS-CoV-2 signaling pathways significantly Stress systemic inflammation Toxicity [DOI] 10.3389/fcimb.2022.726263 PMC 바로가기
15-Year progression to liver cancer in the lack of treatment for lysosomal acid lipase deficiency: A case reportArticle Published on 2022-09-022022-11-16 Journal: Medicine [Category] 변종, [키워드] acid lipase deficiency age cardiovascular complications Case report change characterized Cholangiocarcinoma cholesteryl ester cirrhosis coronavirus disease COVID-19 Deterioration diagnosed Diagnosis enzyme fibrosis Follow-up genetic disorder HCC Hepatocellular carcinoma hepatocyte higher risk IMPROVE individual Kupffer cells Laboratory lack LIPA liver Liver cancer Liver damage Liver function lysosomal male malignancy Mutation Neoplasms nodule pandemic Patient progression reduce reported Sebelipase alfa steatosis therapy tissues treat treated Treatment Triglyceride variant worsening [DOI] 10.1097/MD.0000000000030315 PMC 바로가기
Fibrosis-4 (FIB-4) Index and mortality in COVID-19 patients admitted to the emergency departmentArticle Published on 2022-09-012022-11-15 Journal: Internal and Emergency Medicine [Category] 바이오마커, [키워드] 95% CI 95% confidence interval adjusted hazard ratio ALT Analysis AST AUC cohort study coronavirus COVID-19 COVID-19 patient Cox regression cut-off Department disease Emergency Endpoint FIB-4 fibrosis Fibrosis-4 High-flow oxygen identify increased mortality index Liver damage Liver fibrosis. liver transaminase log-rank test mechanical ventilation Mortality mortality risk Patient performed predict Predictive Prognosis ROC analysis ROC Curve secondary to define were used worse prognosis [DOI] 10.1007/s11739-022-02997-9 PMC 바로가기
Hepatocellular liver injury in hospitalized patients affected by COVID-19: Presence of different risk factors at different time pointsObservational Study Published on 2022-05-012022-10-05 Journal: Digestive and liver disease : official journal of [Category] COVID19(2023년), SARS, 임상, [키워드] Admission affected age alkaline phosphatase alkaline phosphate analyzed C reactive protein Clinical characteristics clinical impact Coronavirus disease 2019 COVID-19 different time point drugs elevated evaluate Factor hepatocellular hepatocellular injury Hospital admission Hospital stay Hospitalization hospitalized patient hypoxia Inflammation intensive care Liver damage Liver function test liver function tests Liver injury Mortality Paracetamol Patient Presence Prevalence progression Remdesivir reported Respiratory failure risk factor SARS-CoV-2 SARS-CoV-2. Switzerland transaminase Treatment was related younger patients [DOI] 10.1016/j.dld.2021.12.014 PMC 바로가기 [Article Type] Observational Study
Prediction Model of Adverse Effects on Liver Functions of COVID-19 ICU PatientsCOVID-19 ICU 환자의 간 기능에 대한 부작용 예측 모델Article Published on 2022-04-252022-09-11 Journal: Journal of Healthcare Engineering [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adverse age ANN assist caused Classifier classifiers collected data country COVID-19 Decision tree develop disease Effect feature function global health Health ICU ICU Patients Illness severity Infection input Laboratory testing liver Liver damage liver diseases liver failure lockdowns machine machine learning machine learning algorithm Machine learning algorithms medical staff Model Naïve Bayes Organ failure outcome patient data patients performed predict prediction Predictive model predictive models risk SARS-CoV-2 severe disease social distancing susceptible SVM tested Topic Treatment variable virus [DOI] 10.1155/2022/4584965 PMC 바로가기 [Article Type] Article
Toxic myopathy and liver damage caused by concomitant therapy with remdesivir, atorvastatin, ezetimibe, and tacrolimus in a renal transplant patient with recently treated SARS-CoV-2 induced pneumonia: A case report최근에 SARS-CoV-2 유발 폐렴을 치료한 신장 이식 환자에서 렘데시비르, 아토르바스타틴, 에제티미브, 타크로리무스 병용 요법으로 인한 독성 근병증 및 간 손상: 증례 보고Case Reports Published on 2022-04-012022-09-11 Journal: Therapeutic apheresis and dialysis : official peer [Category] COVID19(2023년), SARS, 치료제, [키워드] Case report caused concomitant therapy Liver damage Patient Remdesivir renal SARS-CoV-2 toxic treated [DOI] 10.1111/1744-9987.13748 PMC 바로가기 [Article Type] Case Reports
Longitudinal relationship of liver injury with inflammation biomarkers in COVID-19 hospitalized patients using a joint modeling approach공동 모델링 접근법을 사용하는 COVID-19 입원 환자의 염증 바이오마커와 간 손상의 종단 관계Article Published on 2022-04-012022-09-11 Journal: Scientific Reports [Category] 바이오마커, 치료법, 치료제, [키워드] age Alanine Alanine transaminase alkaline phosphatase ALT approach aspartate Aspartate transaminase AST Biomarker blood lymphocyte count C-reactive protein change consecutive patient correlated correlation COVID-19 COVID-19 infection CRP D-dimer decrease died evaluate Generalized hospital Hospitalization hospitalized patient Inflammation inflammation marker inflammation markers interleukin interleukin-6 joint Liver damage Liver disease Liver injury longitudinal lymphocyte Lymphocyte count marker mechanism negative correlation Patient patients with COVID-19 phosphatase plasma positive serum serum C-reactive protein Sex Spain statistical survival Survivors systemic inflammation the patient therapy was used were used [DOI] 10.1038/s41598-022-09290-x PMC 바로가기 [Article Type] Article